It's all about the physiology. In the words of Ernest Starling "The physiology of today is the medicine of tomorrow." Clinical and research practices are informed and guided by the scientific plausibility inferred from physiological modelling of the impossibly complex system of the human body.

Understanding the derivation and appropriate situational application of these models is a central competency in critical care. Improperly simplified heuristics, which often masquerade as understanding, can be misapplied to clinical practice, can appear to work for the wrong reasons or may even do harm.

We research the original publications that have informed the development of the models that we apply in our daily practice and attempt to bundle them up in a narrative that helps you to contextualise and recall the concepts.


A deliberately dense retelling of oxygen cascade physiology.




All your questions answered.